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Three Megastigmane Glycosides from the Leaves ofPterospermum semisagittatum
- Source :
- Pharmaceutical Biology. 41:512-515
- Publication Year :
- 2003
- Publisher :
- Informa UK Limited, 2003.
-
Abstract
- Pterospermum semisagittatum leaves yielded three megastigmane glycosides (Z)-4-[3′-(β-D-glucopyranosyloxy) butylidene]-3,5,5-trimethyl-2-cyclohexen-1-one (1), (E)-4-[3′-(β-D-glucopyranosyloxy)butylidene]-3,5,5-trimethyl-2-cyclohexen-1-one (2) and (E)-4-hydroxy-4-[3′-(β-D-glucopyrano syloxy)butylidene]-3,5,5-trimethyl-2-cyclohexen-1-one (3). Their structures were established by detailed spectroscopic studies. Compound 3 showed a significant insulin releasing effect on rat pancreatic islets.
- Subjects :
- Pharmacology
Pterospermum
chemistry.chemical_classification
biology
Stereochemistry
Pancreatic islets
Pharmaceutical Science
Glycoside
General Medicine
Pharmacognosy
biology.organism_classification
medicine.anatomical_structure
Complementary and alternative medicine
chemistry
Drug Discovery
medicine
Molecular Medicine
Subjects
Details
- ISSN :
- 17445116 and 13880209
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- Pharmaceutical Biology
- Accession number :
- edsair.doi...........c2b9926924a7ae683db2682b6ca00c32