Point-of-care test for early-stage Lyme disease using a multiplexed paper-based assay and machine learning

Authors :: Paul M. Arnaboldi
Raymond J. Dattwyler
Aydogan Ozcan
Linghao Zhang
Hailemariam Teshome
Derek Tseng
Zachary S. Ballard
Omai B. Garner
Hyou-Arm Joung
Jing Wu
Dino Di Carlo
Source :: Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN).
Publication Year :: 2020
Publisher :: Optica Publishing Group, 2020.
Abstract: We report a multiplexed paper-based assay powered by mobile imaging and machine learning for point-of-care diagnosis of Lyme Disease. Blind testing of 96 serum samples showed a sensitivity and specificity of 85.7% and 96.3%, respectively.

Subjects :: Lyme disease
business.industry
Point-of-care testing
medicine
Stage (hydrology)
Paper based
Artificial intelligence
Machine learning
computer.software_genre
medicine.disease
business
computer

Database :: OpenAIRE
Journal :: Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN)
Accession number :: edsair.doi...........c31d5c7ddfb719251c613d7e9080a47e

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