Response to chemotherapy of ulcerative lymphoma of the midface

It has recently been shown that the rare and ominous disease called « lethal midline granuloma » was in fact a true malignant lymphoma in most cases [1]. This disease represents a formidable challenge for the clinician: he has first to reach the diagnosis by the exclusion of dozens of other diseases capable of destroying the center of the face; then he must select a curative treatment together with supportive measures including nutrition therapy in those cachectic patients; and he must manage severe sepsis problems arising from the ulcerated face. We present here our 10-year experience of those ulcerative lymphomas of the midface (ULM).