ChemInform Abstract: A Facile Synthesis of Mannose Tri- and Tetrasaccharide Repeating Units of Fungal Cell-Wall Polysaccharide from Microsporum and Trychophyton Species

A facile synthesis of the trisaccharide α-D-mannopyranosyl-(1→2)-α-D-mannopyranosyl-(1→6)-α-D-mannopyranose and the tetrasaccharide α-D-mannopyranosyl-(1→2)-α-D-mannopyranosyl-(1→6)-α-D-mannopyranosyl-(1→6)-D-mannopyranose, the repeating units of fungal cell-wall polysaccharide from Microsporum gypseum and Trychophyton, was achieved using α-(1→2)-linked disaccharide imidate as the donor. The disaccharide imidate was prepared from the self-condensation of 3,4,6-tri-O-benzoyl-1,2-O-allyloxyethylidene-β-D-mannopyranose.