SAT-195-The novel HBx mutation F30V correlates with HCC in vivo, hampers HBV replicative efficiency and enhances anti-apoptotic activity of HBx N-terminus in vitro

Authors :: Jacopo Vecchiet
Angelica Sacco
Laura Belloni
L. Carioti
Alberto Spanò
Carlo Federico Perno
Pascale Trimoulet
Francesca Ceccherini Silberstein
G.A. Palumbo
Giuseppina Cappiello
Maria Francesca Cortese
Rossana Scutari
Caterina Pasquazzi
Mohammad Alkhatib
Romina Salpini
Gabriele Missale
Carmen Mirabelli
Massimo Levrero
Simona Francioso
Massimo Andreoni
Mario Angelico
Hervé Fleury
Loredana Sarmati
Valentina Svicher
Matteo Surdo
Source :: Journal of Hepatology. 70:e716
Publication Year :: 2019
Publisher :: Elsevier BV, 2019.

Subjects :: N-terminus
HBx
Hepatology
Apoptosis
Chemistry
In vivo
Mutation (genetic algorithm)
Molecular biology
In vitro

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