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Two azulenes produced by the liverwort, Calypogeia azurea, during in vitro culture

Authors :
Jajime Komura
Haruyoshi Konno
Siegfried Huneck
Kenji Katoh
Takaaki Kusumi
Reiji Takeda
Kyosuke Nomoto
Shunji Nakagawara
Source :
Phytochemistry. 31:1667-1670
Publication Year :
1992
Publisher :
Elsevier BV, 1992.

Abstract

Two new sesquiterpenoids, 4-methylazulene-1-carbaldehyde and 4-methylazulene-1-carboxylic acid, were isolated from cultures of Calypogeia azurea . Their structures were established by spectroscopic analysis. The sodium salt of 4-methylazulene-1-carboxylic acid was a naturally occurring water-soluble azulene that displayed anti-inflammatory and anti-ulcer activity.

Details

ISSN :
00319422
Volume :
31
Database :
OpenAIRE
Journal :
Phytochemistry
Accession number :
edsair.doi...........c4fa2d42dd3283b91f893071b9cf0727
Full Text :
https://doi.org/10.1016/0031-9422(92)83125-i