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Long-Term Clinical Outcomes of Patients with no-significant of Transplanted Renal Artery Stenosis

Authors :
Ângelo Amato Vicenzo de Paola
Manoela Linhares Machado Barteczko
Henry Campos Orellana
A C B Faccinetto
Hélio Tedesco Júnior
Gustavo Rocha Feitosa Santos
Adriano Henrique Pereira Barbosa
José Osmar Medina Pestana
Gabriel Kanhouche
Attilio Galhardo
Publication Year :
2021
Publisher :
Research Square Platform LLC, 2021.

Abstract

Background: Transplant Renal Artery Stenosis (TRAS) is the main vascular complication of kidney transplantation. For research and treatment purposes, several authors consider critical renal artery stenosis to be greater than 50%, and percutaneous intervention is indicated in this scenario. However, there are no reports in the current literature on the evolution of patients with less than 50% stenosis.Method: Retrospective study includes data from all patients that were submitted to kidney transplantation and were suspected TRAS after transplantation with stenosis under 50% independent on age, who were referred for angiography at a single center between January 2007 and December 2014. Results: During this period, 6,829 kidney transplants were performed at Hospital do Rim, 313 of them had clinical suspicion of TRAS and 54 were those who presented no-significant stenosis. The average age was 35.93 years old, the predominant gender was male and most individuals (94.4%) were submitted to dialysis before transplantation. Transplants, in most cases in this group, occurred from a deceased donor, 66.7%. The time between transplantation and angiography was less than one year in 79.6% of patients and all presented no-significant TRAS. Creatinine levels, Systolic Blood Pressure, Diastolic Blood Pressure and the glomerular filtration rate improved over the long term. The outcomes found were death and renal loss.Conclusion: Age, sex and ethnic group of patients are factors that did not interfere with the frequency of renal artery stenosis. The outcomes showed that in the long term most patients evolve well, and have improved quality of life and kidney function, although there are cases of death and kidney loss.

Details

Database :
OpenAIRE
Accession number :
edsair.doi...........c5c76295db910581e8d37174dbf2b969
Full Text :
https://doi.org/10.21203/rs.3.rs-388038/v1