Additional file 21: of HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer

Kaplan-Meier survival estimates in patients in TCGA set whose tumours had a high (a) and a low (b) HOTAIR DNA methylation score. Survival analysis was performed according to the type of chemotherapy patients received: carboplatin based (Carboplatin), carboplatin-cisplatin (Carbo-Cisp) or cisplatin chemotherapy (Cisplatin). Hazard ratios (HR) and P values were calculated comparing cisplatin- with carboplatin-based (non-cisplatin-containing) chemotherapy regimens. (PDF 8 kb)