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Urodynamic Findings in Pediatric Spastic Cerebral Palsy: Retrospective Study From a Single Center

Authors :
Sen Li
Bo Xiao
Qijia Zhan
Min Wei
Huizhen Sun
Baojun Gu
Wenbin Jiang
Fang Chen
Publication Year :
2021
Publisher :
Research Square Platform LLC, 2021.

Abstract

Objective To investigate the urodynamic study (UDS) result in pediatric patients with spastic cerebral palsy (CP). Material and methods Medical records of CP with pre-operative UDS results underwent selective dorsal rhizotomy (SDR) from Jan. 2020 to May. 2021 were retrospectively reviewed. Results Fifty-seven cases with spastic CP were included in the study. Among these cases, 46 were ambulatory and 11 were non-ambulatory. Average gross motor function measure - 66 (GMFM - 66) score was 62.16 ± 11.39. Reduced bladder capacity was seen in 49.12% of these cases and cases with lower GMFM - 66 score had a higher incidence rate of having low bladder capacity (p < 0.01). Detrusor overactivity (DO) was shown in 33.33% of patients. Cases with younger age had higher prevalence of DO (p < 0.05). Meanwhile, more non-ambulant patients had DO (p < 0.05). Increased post-voiding residual (PVR) was seen in 21.05% of cases. Those with higher average threshold in sphincter-associated input spinal nerve roots (rootlets) had higher rate of having abnormal PVR (p < 0.05). Conclusion Abnormal UDS results were prevalent in pediatric spastic CP. Motor function, age and threshold of their sphincter-associated spinal nerve rootlets were related to the abnormal UDS results.

Details

Database :
OpenAIRE
Accession number :
edsair.doi...........c71077a58a80f9fd977b720b08a7c193
Full Text :
https://doi.org/10.21203/rs.3.rs-990667/v1