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Molecular Initiating Events of Bisphenols on Androgen Receptor-Mediated Pathways Provide Guidelines for in Silico Screening and Design of Substitute Compounds

Authors :
Yu Hongxia
Xiaowei Zhang
Xiaoxiang Wang
Chen Qinchang
Tan Haoyue
John P. Giesy
Wei Shi
Si Wei
Source :
Environmental Science & Technology Letters. 6:205-210
Publication Year :
2019
Publisher :
American Chemical Society (ACS), 2019.

Abstract

Bisphenols (BPs) have the potential to interfere with the androgen receptor (AR). However, in silico screening and substitute design were difficult because little was known about the mechanisms by ...

Details

ISSN :
23288930
Volume :
6
Database :
OpenAIRE
Journal :
Environmental Science & Technology Letters
Accession number :
edsair.doi...........c72e7190826646b98c9e68d60556eb13