Synthesis of amylostatin (XG), α-glucosidase inhibitor with basic pseudotrisaccharide structure

Authors :: Hiroyoshi Kuzuhara
Nobuo Sakairi
Source :: Tetrahedron Letters. 23:5327-5330
Publication Year :: 1982
Publisher :: Elsevier BV, 1982.
Abstract: The basic pseudotrisaccharide ( 1 constituting the common and essential building block of several α-glucosidase inhibitors of microbial origin was synthesized by coupling two synthons: the chiral cyclohexyl halide ( 11 ) and the 4′-amino-4′-deoxy-disaccharide ( 14 ).

Subjects :: Chemistry
Stereochemistry
α glucosidase
Organic Chemistry
Drug Discovery
Synthon
Biochemistry
Combinatorial chemistry

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