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Hydroxycarboxylic acid receptors in GtoPdb v.2023.1
- Source :
- IUPHAR/BPS Guide to Pharmacology CITE. 2023
- Publication Year :
- 2023
- Publisher :
- Edinburgh University Library, 2023.
-
Abstract
- The hydroxycarboxylic acid family of receptors (ENSFM00500000271913, nomenclature as agreed by the NC-IUPHAR Subcommittee on Hydroxycarboxylic acid receptors [36, 12]) respond to organic acids, including the endogenous hydroxy carboxylic acids 3-hydroxy butyric acid and L-lactic acid, as well as the lipid lowering agents nicotinic acid (niacin), acipimox and acifran [53, 60, 65]. These receptors were provisionally described as nicotinic acid receptors, although nicotinic acid shows submicromolar potency at HCA2 receptors only and is unlikely to be the natural ligand [60, 65].
- Subjects :
- General Medicine
General Chemistry
Subjects
Details
- ISSN :
- 26331020
- Volume :
- 2023
- Database :
- OpenAIRE
- Journal :
- IUPHAR/BPS Guide to Pharmacology CITE
- Accession number :
- edsair.doi...........c8424a24561efca02ad12bf8e01ad7af