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Iodine-Mediated Diastereoselective Cyclopropanation of Arylidene Malononotriles by 2,6-Dimethylquinoline

Authors :
Stavroula Skoulika
Reza Hosseinpour
Issa Yavari
Source :
Synlett. 26:380-384
Publication Year :
2015
Publisher :
Georg Thieme Verlag KG, 2015.

Abstract

A novel iodine-mediated reaction of 2,6-dimethylquinoline with Knoevenagel condensation products of malononitrile with benzaldehydes, leading to a facile, one-pot synthesis of 2-aryl-3-(6-methylquinolin-2-yl)cyclopropane-1,1-dicarbonitriles, in moderate to good yields, is described.

Details

ISSN :
14372096 and 09365214
Volume :
26
Database :
OpenAIRE
Journal :
Synlett
Accession number :
edsair.doi...........c92c38e9b504cefc6e177404c380ac7c
Full Text :
https://doi.org/10.1055/s-0034-1379496