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Dioscin alleviates hashimoto’s thyroiditis by regulating the SUMOylation of IRF4 to promote CD4+CD25+Foxp3+ treg cell differentiation

Authors :
Wen Weibo
Sun Yumeng
Qiao Nan
Cao Yongjun
Jin Xiaowen
Source :
Autoimmunity. 54:51-59
Publication Year :
2020
Publisher :
Informa UK Limited, 2020.

Abstract

Dioscin has been used as a treatment for Hashimoto’s thyroiditis (HT) in China. However, the molecular mechanisms governing the modes of action of dioscin have not been elucidated. In this study, f...

Details

ISSN :
1607842X and 08916934
Volume :
54
Database :
OpenAIRE
Journal :
Autoimmunity
Accession number :
edsair.doi...........c9b7e1e391ef7d6fd21ee896d277cedf
Full Text :
https://doi.org/10.1080/08916934.2020.1855428