ChemInform Abstract: A General Method for N-Methylation of Amines and Nitro Compounds with Dimethylsulfoxide

Authors :: Yawen Wei
Xue Jiang
Chao Wang
Jianliang Xiao
Dong Xue
Zhao-Tie Liu
Source :: ChemInform. 45
Publication Year :: 2014
Publisher :: Wiley, 2014.
Abstract: DMSO methylates a broad range of amines in the presence of formic acid, providing a novel, green and practical method for amine methylation. The protocol also allows the one-pot transformation of aromatic nitro compounds into dimethylated amines in the presence of a simple iron catalyst.

Subjects :: chemistry.chemical_compound
General method
chemistry
Formic acid
Nitro
Organic chemistry
Amine gas treating
General Medicine
Methylation
N methylation
Iron catalyst

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