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Hemodynamic, Echocardiographic, and Exercise-Related Effects of the HeartWare Left Ventricular Assist Device in Advanced Heart Failure

Authors :
Adam K McDiarmid
Gareth Parry
Thasee Pillay
Stephan Schueler
Brian Gordon
Neil Wrightson
N. Robinson-Smith
Guy A. MacGowan
Source :
Congestive Heart Failure. 19:11-15
Publication Year :
2012
Publisher :
Wiley, 2012.

Abstract

The aim of this study was to determine the effects of the HeartWare left ventricular assist device (HVAD) (HeartWare International, Inc, Framingham, MA) on hemodynamics, ventricular function, and exercise capacity. Between July 2009 and March 2011, 46 patients with advanced heart failure had implantation of the HVAD. Of these patients, 30 had subsequent assessments for transplantation and these patients formed the study cohort. Thirty patients had assessments at a mean of 201±86 days and 13 went on to have a second assessment at 351±86 days. There were marked improvements in hemodynamics and exercise capacity at both assessments, with significant decreases in right and left heart filling pressures; increases in cardiac index, New York Heart Association class, and peak exercise oxygen consumption; and reduction in pulmonary vascular resistance (all P

Details

ISSN :
15275299
Volume :
19
Database :
OpenAIRE
Journal :
Congestive Heart Failure
Accession number :
edsair.doi...........cb2a3f3d732d931ba395e145d92a1314
Full Text :
https://doi.org/10.1111/j.1751-7133.2012.00302.x