Effect of echo-sampling strategy on the accuracy of out-of-phase and in-phase multiecho gradient-Echo MRI hepatic fat fraction estimation

Purpose To assess the effect of echo-sampling strategy on the accuracy of out-of-phase (OP) and in-phase (IP) multi-echo gradient-echo magnetic resonance imaging (MRI) hepatic fat fraction (FF) estimation, using MR spectroscopy (MRS) proton density FF (PDFF) as a reference standard.