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Towards Human Translation of Lentiviral Airway Gene Delivery for Cystic Fibrosis: A One-Month CFTR and Reporter Gene Study in Marmosets

Authors :
Mathew Smith
John W. Finnie
Nathan Rout-Pitt
Nigel Farrow
Lewis Vaughan
Patricia Cmielewski
Tim Kuchel
Martin Donnelley
Emma Knight
Chris Christou
David Parsons
Juliette M. K. M. Delhove
Source :
Human Gene Therapy. 32:806-816
Publication Year :
2021
Publisher :
Mary Ann Liebert Inc, 2021.

Abstract

Gene therapy continues to be a promising contender for the treatment of cystic fibrosis (CF) airway disease. We have previously demonstrated that airway conditioning with lysophosphatidylcholine (L...

Details

ISSN :
15577422 and 10430342
Volume :
32
Database :
OpenAIRE
Journal :
Human Gene Therapy
Accession number :
edsair.doi...........cddabbb6c385c826565768e9013ba01f