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Sodium Iodide/Hydrogen Peroxide-Mediated Oxidation/Lactonization for the Construction of Spirocyclic Oxindole-Lactones
- Source :
- Advanced Synthesis & Catalysis. 358:2873-2877
- Publication Year :
- 2016
- Publisher :
- Wiley, 2016.
-
Abstract
- The sodium iodide/hydrogen peroxide-mediated oxidation/lactonization of indolepropionic acids was achieved, affording the corresponding spirocyclic oxindole-lactones in moderate to high yields. This metal-free procedure features mild reaction conditions, non-toxicity and easy handling, with hydrogen peroxide (H2O2) as a clean oxidant.
Details
- ISSN :
- 16154150
- Volume :
- 358
- Database :
- OpenAIRE
- Journal :
- Advanced Synthesis & Catalysis
- Accession number :
- edsair.doi...........cdf2803ac9331cfa3f4ebda55be9c3e9