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Sodium Iodide/Hydrogen Peroxide-Mediated Oxidation/Lactonization for the Construction of Spirocyclic Oxindole-Lactones

Authors :
Wangsheng Sun
Guofeng Li
Junqiu Xie
Jiecheng Xu
Liang Hong
Liwu Huang
Rui Wang
Source :
Advanced Synthesis & Catalysis. 358:2873-2877
Publication Year :
2016
Publisher :
Wiley, 2016.

Abstract

The sodium iodide/hydrogen peroxide-mediated oxidation/lactonization of indolepropionic acids was achieved, affording the corresponding spirocyclic oxindole-lactones in moderate to high yields. This metal-free procedure features mild reaction conditions, non-toxicity and easy handling, with hydrogen peroxide (H2O2) as a clean oxidant.

Details

ISSN :
16154150
Volume :
358
Database :
OpenAIRE
Journal :
Advanced Synthesis & Catalysis
Accession number :
edsair.doi...........cdf2803ac9331cfa3f4ebda55be9c3e9