Approach to synthesis of 8-azasteroids Communication 3. Condensation of 3,4-dihydroisoquinolines with derivatives of dehydroacetic acid

1. The condensation of 3,4-dihydroisoquinolines with dehydroacetic acid derivatives proceeds in two principal directions: with a retention and an opening of the pyrone ring. 2. The condensation with 5,6-dihydrodehydroacetic acid leads to the formation of the vinylog lactams of the benzo[a]pyrano[f]quinolizine series, the enaminodicarbonyl grouping of which has a high reactivity.