Cardiovascular Malformations in the Conotruncal Anomaly Face Syndrome

In 1976, we reported a peculiar facial appearance [1] specifically related to conotruncal anomalies of the heart that was thus named “conotruncal anomaly face” (CTAF) and was characterized by lateral displacement of inner canthi, narrow palpebral fissures, flat nasal bridge, bloated eyelids, small mouth, hypoplastic mandibula, deformed earlobe, and nasal voice with velopharyngeal insufficiency [1–3].