ChemInform Abstract: Synthesis, Structure and H+/K+-ATPase Inhibitory Activity of Novel Triazolyl Substituted Tetrahydrobenzofuran Derivatives via One-Pot Three-Component Click Reaction

Authors :: Nianyu Huang
Lei Jin
Hubiao Fang
Kun Zou
Zaigang Luo
Junzhi Wang
Source :: ChemInform. 44
Publication Year :: 2013
Publisher :: Wiley, 2013.
Abstract: A CuI-catalyzed three-component alkyne-azide cycloaddition in the presence of an excess of secondary amine is used for the synthesis of triazolyl-substituted tetrahydrobenzofuran derivatives.

Subjects :: biology
Chemistry
Stereochemistry
ATPase
Triazole derivatives
Click chemistry
biology.protein
Amine gas treating
General Medicine
Inhibitory postsynaptic potential
Cycloaddition

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