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Synthesis of 6-Oxo-1,2,3,4,6,7,12,12b -octahydroindolo[2,3-a ]quinolizine

Authors :
Randall B. Nelson
David C. Tompkins
Lloyd J. Dolby
Gordon W. Gribble
Laurence W. Reilly
Source :
Journal of Heterocyclic Chemistry. 55:1048-1052
Publication Year :
2018
Publisher :
Wiley, 2018.

Abstract

An efficient synthesis of 6-oxo-1,2,3,4,5,7,12,12b-octahydroindolo[2,3-α]quinolizine from 2-acetylpyridine and phenylhydrazine is described. This derivative of the natural alkaloid desbromoarborescidine A is an important entry point to the sarpagine-vobasine family of plant alkaloids.

Details

ISSN :
0022152X
Volume :
55
Database :
OpenAIRE
Journal :
Journal of Heterocyclic Chemistry
Accession number :
edsair.doi...........d677b46ed7565a60637b0181baecd109
Full Text :
https://doi.org/10.1002/jhet.3130