Bepirovirsen, antisense oligonucleotide (ASO) against hepatitis B virus (HBV), harbors intrinsic immunostimulatory activity via Toll-like receptor 8 (TLR8) preclinically, correlating with clinical efficacy from the Phase 2a study

Authors :: Shihyun You
Jared Delahaye
Megan Ermler
Jennifer Singh
William Jordan
Avijit Ray
Nicholas Galwey
Daren Austin
Dickens Theodore
Melanie Paff
Source :: Journal of Hepatology. 77:S873-S874
Publication Year :: 2022
Publisher :: Elsevier BV, 2022.

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