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Formulation and Evaluation of Herbal Ointment of Berberis aristata for Inhibition of Psoriasis-like Symptoms

Authors :
Alankar Shrivastav
Arun Kumar Mishra
Ashessh Kumar Gupta
Source :
Biosciences Biotechnology Research Asia. 19:971-977
Publication Year :
2022
Publisher :
Oriental Scientific Publishing Company, 2022.

Abstract

To prepare an herbal ointment using an ethanolic extract of Berberis aristata and assess the anti-psoriatic effectiveness of the finished product. We were able to make multiple ointments that were each categorized as F-1, F-2, and F-3 by adding varying concentrations of stearic acid and cetyl alcohol by learning about various formulation types, such as oil in water. The analysis of many factors, including pH, viscosity, spreadability, and stability, was used to evaluate all formulations. A formulation of ethanolic extract (F-3) showed antipsoriatic action. No evidence of a separate phase or ease of removal was found in any of the formations, but they all demonstrated good spreadability, consistency, appearance, and pH. Additionally, during irritancy trials, the formulation F-3 did not cause redness, oedema, erythema, or irritation. The use of this formulation on the skin is safe. As a result, the study implies that the extract's and the ointment's base's compositions are safer and more stable, however, they might also have synergistic effects.

Details

ISSN :
24562602 and 09731245
Volume :
19
Database :
OpenAIRE
Journal :
Biosciences Biotechnology Research Asia
Accession number :
edsair.doi...........d74e791d066c5d8c73a9c5849306271b
Full Text :
https://doi.org/10.13005/bbra/3046