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A phase 1/2, multicenter, dose-escalation and expansion study of combination therapy with venetoclax, daratumumab, and dexamethasone (with and without bortezomib) in subjects with relapsed or refractory multiple myeloma
- Source :
- Journal of Clinical Oncology. 36:TPS8061-TPS8061
- Publication Year :
- 2018
- Publisher :
- American Society of Clinical Oncology (ASCO), 2018.
-
Abstract
- TPS8061Background: Despite the introduction of new compounds to manage relapsed/refractory (R/R) multiple myeloma (MM) over the last decade, none are curative. Trials investigating novel agents or ...
- Subjects :
- Oncology
Cancer Research
medicine.medical_specialty
Combination therapy
Bortezomib
business.industry
Venetoclax
Daratumumab
medicine.disease
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
chemistry
Refractory
030220 oncology & carcinogenesis
Internal medicine
medicine
Dose escalation
business
Dexamethasone
Multiple myeloma
030215 immunology
medicine.drug
Subjects
Details
- ISSN :
- 15277755 and 0732183X
- Volume :
- 36
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Oncology
- Accession number :
- edsair.doi...........d883e8a93377ef9b7c5f736bd58fff04
- Full Text :
- https://doi.org/10.1200/jco.2018.36.15_suppl.tps8061