ChemInform Abstract: Synthesis of 2-Deoxy-4-O-phosphono-3-O-tetradecanoyl-2-((3R)- and (3S)- 3-tetradecanoyloxytetradecanamido)-D-glucose: A Diastereoisomeric Pair of 4-O-Phosphono-D-glucosamine Derivatives (GLA-27) Related to Bacterial Lipid A

The diastereoisomeric, 4-O-phosphono- d -glucosamine derivatives named in the title have been synthesized, starting from benzyl 2-amino-2-deoxy-4,6-O-isopropylidene-β- d -glucopyranoside and (3RS)-3-hydroxytetradecanoic acid.