GW28-e1205 Activin receptor-like kinase 4 deficiency attenuates atrial remodeling and vulnerability to atrial fibrillation induced by pressure overload in mice

Activin receptor-like kinase 4 (ALK4), a downstream receptor of transforming growth factor-β superfamily, is highly expressed in the mammal heart. We recently reported that ALK4 is upregulated in pressure-overloaded heart and ALK4 haplodeficiency attenuated the pressure overload-induced cardiac