Hepatoprotective potential of ethanolic and aqueous extract of flowers of Sesbania grandiflora (Linn) induced by CCl4

Objective To investigate the hepatoprotective activity of ethanolic and aqueous extract of Sesbania grandiflora (Linn) flower in CCl4 induced hepatotoxicity models in rats. Methods The ethanolic and aqueous extract of Sesbania grandiflora (Linn) flower are screened for its hepatoprotective activity in CCl4 (0.5 ml/kg, i.p) induced liver damage in Swiss albino rats at a dose of 200 mg/kg bw. Results The ethanolic and aqueous extract of Sesbania grandiflora (Linn) flower significantly (P Conclusions The ethanolic extract at doses of 250 and 500 mg/kg, p.o. and aqueous extract at a dose of 500 mg/kg, p.o. of Sesbania grandiflora (Linn) flower have significant effect on the liver of CCl4 induced hepatotoxicity animal models.