Effects of the influence of copper and zinc on living organisms (literature review)

Introduction. Scientists from Horbachevsky Ternopil National Medical University, Ternopil, and various countries, including state laboratories, have thoroughly studied the biological significance of copper and zinc ions in the body for many years. Nevertheless, the value of the shortage or excess of these metals and their compounds in the body remains mostly underestimated for health. Purpose of work: to study the pathogenesis of traumatic disease occurring due to an imbalance of copper and zinc in the body. Methods. Bibliosemantic and analytical methods were used. A literature search was conducted for the following queries as zinc, copper, heavy metals, negative impact. The investigation was performed with PubMed, Scopus, Web of Science, and Google Scholar for various articles. All publications have been analyzed and included in this review. The importance of these metals’ lack or excess and their compounds in the body remains mostly underestimated. Features of the pathogenesis of many diseases occurring due to imbalance of copper and zinc in the body have also been unexplored. The traumatic disorder was no exception, as this was not considered in experimental and clinical medicine. Conclusion. From the analysis of the available scientific literature, no messages were found about the features of the course of traumatic disease in conditions of excessive intake of copper and zinc ions in the body. We can only assume that a violation of the functional ability of the liver, lungs, brain and other organs that occurs against the background of heavy metal ion damage creates an unfavorable background for the occurrence of a serious injury.