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The Functional Role of Garlic and Bioactive Components in Cardiovascular and Cerebrovascular Health: What We Do Know
- Source :
- Journal of Biosciences and Medicines. :28-42
- Publication Year :
- 2016
- Publisher :
- Scientific Research Publishing, Inc., 2016.
-
Abstract
- Cardiovascular disease is a complex and multifactorial disease strongly associated with hypercholesterolemia, hypertension, reduced ?brinolysis, increased blood-clotting time and increased platelet aggregation. Among other confounding factors, oxidative damage is a major factor in cardiovascular and cerebrovascular diseases. The use of garlic in folkloric medicine highlights the potential role in either preventing or delaying cardiovascular disease. Contemporary research reveals how garlic and bioactive components modulate the risk factors of cardiovascular and cerebrovascular diseases thus tending towards validating a measure of folkloric claims concerning the functional efficacy of garlic. This review seeks to elucidate contemporary research attempt towards the validation of the role of garlic and bioactive components, mechanisms of action involved and to define its ultimate role in the prevention and treatment of cardiovascular and cerebrovascular diseases. Some contradictory claims exist possibly due to the use of different experimental protocols/formulations/dosages of garlic. Overwhelming commonality of positive cardiovascular and cerebro-vascular responses reside among research studies thus offering compelling evidence in supports of the bene?cial health effects of garlic and components.
- Subjects :
- 0301 basic medicine
Functional role
Pathology
medicine.medical_specialty
business.industry
Multifactorial disease
food and beverages
Disease
030204 cardiovascular system & hematology
Bioinformatics
Increased Platelet Aggregation
Oxidative damage
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
Research studies
medicine
business
Subjects
Details
- ISSN :
- 2327509X and 23275081
- Database :
- OpenAIRE
- Journal :
- Journal of Biosciences and Medicines
- Accession number :
- edsair.doi...........dd00b5014490af85402a63f234c464a0