Comment on Law et al. Suboptimal Nocturnal Glucose Control Is Associated With Large for Gestational Age in Treated Gestational Diabetes Mellitus. Diabetes Care 2019;42:810–815

We were interested in the article by Law et al. (1), who reported that high nocturnal glucose, as recorded by continuous glucose monitoring (CGM), was associated with large for gestational age (LGA) newborns in women with gestational diabetes mellitus (GDM). The nocturnal hyperglycemia was not detected by fasting self-monitored blood glucose (SMBG), which argues for performing CGM in GDM. The figure in the article nicely depicts how nocturnal hyperglycemia was missed by conventional SMBG: as underlined by the authors, the difference in nocturnal CGM glucose between mothers of LGA infants and those of normal-weight newborns was a peak displayed at 0200–0300 h, which then progressively declined to become nonsignificant when the women …