ETV6-NTRK3 is a common chromosomal rearrangement in radiation-associated thyroid cancer

Authors :: Mark P. Little
Miao Zhang
Yuri E. Nikiforov
Mykola Tronko
Maureen Hatch
Tetiana Bogdanova
Lindsey M. Kelly
Kiyohiko Mabuchi
Marina N. Nikiforova
Pengyuan Liu
Alina V. Brenner
Rebecca J. Leeman-Neill
Viktoria N. Evdokimova
Ning J. Yue
Liudmyla Y. Zurnadzy
Source :: Cancer. 120:799-807
Publication Year :: 2013
Publisher :: Wiley, 2013.
Abstract: Background Our previous analysis of papillary thyroid carcinomas (PTC) from the Ukrainian-American cohort exposed to 131I from the Chernobyl accident found RET/PTC rearrangements and other driver mutations in 60% of tumors.

Subjects :: endocrine system
Cancer Research
Pathology
medicine.medical_specialty
endocrine system diseases
business.industry
Point mutation
Environmental exposure
Chromosomal rearrangement
medicine.disease
Chernobyl Nuclear Accident
humanities
Thyroid carcinoma
Fusion gene
ETV6
Oncology
Medicine
business
Thyroid cancer

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