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Incremental Value of Gait Speed in Predicting Prognosis of Older Adults With Heart Failure

Authors :
Giovanni Pulignano
Donatella Del Sindaco
Andrea Di Lenarda
Gianfranco Alunni
Michele Senni
Luigi Tarantini
Giovanni Cioffi
Maria Denitza Tinti
Giulia Barbati
Giovanni Minardi
Massimo Uguccioni
Giovanni Gaschino
Giulia Russo
Donatella Radini
Kira Stellato
Adriano Murrone
Cinzia Zuchi
Stefano Tolone
Luca Monzo
Source :
JACC: Heart Failure. 4:289-298
Publication Year :
2016
Publisher :
Elsevier BV, 2016.

Abstract

Objectives The aim of this study was to assess the relationship between gait speed and the risk for death and/or hospital admission in older patients with heart failure (HF). Background Gait speed is a reliable single marker of frailty in older people and can predict falls, disability, hospital admissions, and mortality. Methods In total, 331 community-living patients ≥70 years of age (mean age 78 ± 6 years, 43% women, mean ejection fraction 35 ± 11%, mean New York Heart Association functional class 2.7 ± 0.6) in stable condition and receiving optimized therapy for chronic HF were prospectively enrolled and followed for 1 year. Gait speed was measured at the usual pace over 4 m, and cutoffs were defined by tertiles: ≤0.65, 0.66 to 0.99, and ≥1.0 m/s. Results There was a significant association between gait speed tertiles and 1-year mortality: 38.3%, 21.9%, and 9.1% (p Conclusions Gait speed is independently associated with death, hospitalization for HF, and all-cause hospitalization and improves risk stratification in older patients with HF evaluated using the Cardiac and Comorbid Conditions Heart Failure score. Assessment of frailty using gait speed is simple and should be part of the clinical evaluation process.

Details

ISSN :
22131779
Volume :
4
Database :
OpenAIRE
Journal :
JACC: Heart Failure
Accession number :
edsair.doi...........df0985acb5ce9709caf6e5cffcb13bdf
Full Text :
https://doi.org/10.1016/j.jchf.2015.12.017