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Remarkable effect of lithium bromide in the enantioselective protonation with α-sulfinyl alcohols

Authors :
Pedro Aleman
Luis R. Domingo
Gregorio Asensio
Mercedes Medio-Simón
Source :
Tetrahedron Letters. 39:3277-3280
Publication Year :
1998
Publisher :
Elsevier BV, 1998.

Abstract

The favourable effect of lithium bromide enhancing the facial enantioselectivity in the protonation of methyl tetralone enolate with α-sulfinyl alcohols is described. Theoretical calculations allow to propose a model to explain the stereochemical course of the protonation reaction.

Details

ISSN :
00404039
Volume :
39
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........dfdc1345ee22a25f2126bf84ef78b12f
Full Text :
https://doi.org/10.1016/s0040-4039(98)00469-9