Synthesis and sar of 2h-1,2,4-benzothiadiazine-1,1-dioxide-3- carboxylic acid derivatives as novel potent glycine antagonists of the nmda receptor-channel complex

Authors :: Jean-Claude Aloup
Jean-Marie Stutzmann
Michel Cheve
Michel Barreau
Francois Audiau
Alain Boireau
John Randle
Jacques Lavayre
Serge Mignani
J.‐C. Blanchard
Dominique Damour
Adam Doble
Gilles Dutruc-Rosset
J. Rataud
Patrick Jimonet
Andrees Bohme
Source :: Bioorganic & Medicinal Chemistry Letters. 4:2735-2740
Publication Year :: 1994
Publisher :: Elsevier BV, 1994.

Subjects :: chemistry.chemical_classification
Channel complex
Chemistry
Stereochemistry
Carboxylic acid
Organic Chemistry
Clinical Biochemistry
Pharmaceutical Science
Glycine receptor antagonist
Biochemistry
chemistry.chemical_compound
Benzothiadiazine
Drug Discovery
Molecular Medicine
NMDA receptor
Molecular Biology

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