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Corrigendum to 'Syndecan-2 and -4 expressed on activated primary human CD4+ lymphocytes can regulate T cell activation' [Mol. Immunol. 45 (10) (2008) 2905–2919]

Authors :
Trini Teixé
Manuel Reina
Ramon Vilella
Enric Espel
Patricia Nieto-Blanco
Pablo Engel
Source :
Molecular Immunology. 51:368
Publication Year :
2012
Publisher :
Elsevier BV, 2012.

Abstract

The author regrets that in the above published paper the following error occurred:In Fig. 3 of the paper cited above, trace amounts of protein A in the affinity chromatography-purified anti-syndecan-2 mAb 186C(protein Awhichleachedfromtheaffinityresin),whosepresencewentunnoticed,interferedwiththeanti-CD3 mAb(mouseIgG2a)usedto stimulate the T cells. Based on the original results we suggested that syndecan-2 could have an inhibitory effect on T cells. However, re-evaluation ofsimilarexperimentswithproteinA-freeanti-syndecan-2mAb186CindicatesthatthemAbdoesnotinhibitT-cellproliferationor IL-2 mRNA synthesis.

Details

ISSN :
01615890
Volume :
51
Database :
OpenAIRE
Journal :
Molecular Immunology
Accession number :
edsair.doi...........e078d60371359f5fb90f73d78e225d17
Full Text :
https://doi.org/10.1016/j.molimm.2012.05.002