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Diagnostic Value of Estimating the Ratio of Serum Free Triiodothyronine to Free Thyroxine in Differenti-ating Graves' Disease from Thyroiditis
- Source :
- Suez Canal University Medical Journal. 23:135-142
- Publication Year :
- 2020
- Publisher :
- Egypts Presidential Specialized Council for Education and Scientific Research, 2020.
-
Abstract
- Background: As the treatment approaches of Graves’ disease (GD) and thyroiditis are different, the differential diagnosis is essential. Aim: To assess the diagnostic value of free triiodothyronine (FT3) to free thyroxine (FT4) ratio for differentiation between GD and destructive thyroiditis. Subjects and Methods: The present study was conducted on 100 newly diagnosed thyrotoxicosis patients; 61 with thyroiditis (group 1) and 39 with GD (group 2) and 20 healthy, age-matched subjects representing a control group (Group 3). All participants underwent medical history taking and clinical examination, serum levels of thyroid-stimulating hormone (TSH), FT3, and FT4 were measured, Technetium 99m thyroid Scan was done to all recruited patients. Results: The present results recorded significant increases in FT3, FT4, and decreases in TSH levels in Graves’ disease group than in the thyroiditis group. There was a statistically significant difference between the study groups regarding FT3/FT4 ratio, which was lower in thyroiditis group than in Graves’ disease group (0.21± 0.03 in group 1 vs 0.35±0.18 in group 2, p-value
- Subjects :
- endocrine system
medicine.medical_specialty
Triiodothyronine
endocrine system diseases
medicine.diagnostic_test
business.industry
Graves' disease
Physical examination
medicine.disease
Gastroenterology
Thyroiditis
Internal medicine
medicine
Medical history
Differential diagnosis
business
Technetium-99m
Hormone
Subjects
Details
- ISSN :
- 20902581
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Suez Canal University Medical Journal
- Accession number :
- edsair.doi...........e07ca0af4b494bb9100265dc38adf9bd