Analysis of the association between the LUM rs3759223 variant and high myopia in a Japanese population

PURPOSE Many studies have investigated the relationship of the lumican gene (LUM) rs3759223 variant with the risk of high myopia, but the results have been inconsistent and inconclusive. In this study, we investigated whether LUM rs3759223 is associated with high myopia in a Japanese population. METHODS We recruited 1,585 Japanese patients with high myopia (spherical equivalent [SE]