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Effects of Coenzyme Q10 on the Expression of Genes involved in Lipid Metabolism in Laying Hens
- Source :
- Korean Journal of Poultry Science. 43:47-54
- Publication Year :
- 2016
- Publisher :
- The Korean Society of Poultry Science, 2016.
-
Abstract
- Department of Animal Science and Biotechnology, Gyeongnam National University of Science and Technology, Jinju 52725, Korea ABSTRACT The aim of this study was to investigate the expression patterns of key genes involved in lipid metabolism in response to dietary Coenzyme Q10 (CoQ10) in hens. A total of 36 forty week-old Lohmann Brown were randomly allocated into 3 groups consisting of 4 replicates of 3 birds. Laying hens were subjected to one of following treatments: Control (BD, basal diet), T1 (BD+ CoQ10 100 mg/kg diet) and T2 (BD+ micellar of CoQ10 100 mg/kg diet). Birds were fed ad libitum a basal diet or the basal diet supplemented with CoQ10 for 5 weeks. Total RNA was extracted from the liver for quantitative RT-PCR. The mRNA levels of HMG-CoA reductase(HMGCR) and sterol regulatory element-binding proteins(SREBP)2 were decreased more than 3050% in the liver of birds fed a basal diet supplemented with CoQ10 (p
- Subjects :
- Coenzyme Q10
medicine.medical_specialty
Cholesterol
Lipid metabolism
Reductase
Biology
Sterol
Sterol regulatory element-binding protein
chemistry.chemical_compound
Basal (phylogenetics)
Endocrinology
chemistry
Internal medicine
medicine
lipids (amino acids, peptides, and proteins)
Liver X receptor
Subjects
Details
- ISSN :
- 12256625
- Volume :
- 43
- Database :
- OpenAIRE
- Journal :
- Korean Journal of Poultry Science
- Accession number :
- edsair.doi...........e215f5e4043db92fabcf4fe48b3322ff