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Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis: a study of the Osaka Lymphoma Study Group

Authors :
Masaharu Kohara
Mona A A Zaki
Haruo Sugiyama
Yuzuru Kanakura
Katsuyuki Aozasa
Hiroyasu Ogawa
Masayuki Hino
Hiroshi Inagaki
Eiichi Morii
Naoki Wada
Shosaku Nomura
Itaru Matsumura
Source :
Histopathology. 60:924-932
Publication Year :
2012
Publisher :
Wiley, 2012.

Abstract

Wada N, Zaki M A A, Kohara M, Ogawa H, Sugiyama H, Nomura S, Matsumura I, Hino M, Kanakura Y, Inagaki H, Morii E & Aozasa K (2012) Histopathology 60, 924–932 Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis: a study of the Osaka Lymphoma Study Group Aims: ]Diffuse large B cell lymphoma (DLBCL) occasionally shows an interfollicular pattern of proliferation (DLBCL-IF) preserving lymphoid follicles. In this study, clinicopathological findings in 31 cases of DLBCL-IF were analysed. Methods and results: The study group comprised 20 males and 11 females, with ages ranging from 41 to 87 (median 69) years. The primary site was lymph node in 25 cases, and unknown in six due to advanced stage at diagnosis. Eight cases were clinical Stage I, 10 were Stage II, four Stage III, and nine Stage IV. A polymorphous pattern of proliferation containing large B cells and inflammatory cells was found in about 60% of cases. The overall survival rate of the DLBCL-IF patients was better than that of a DLBCL control group (log-rank test; P

Details

ISSN :
03090167
Volume :
60
Database :
OpenAIRE
Journal :
Histopathology
Accession number :
edsair.doi...........e290d9a61427d38537eb4cc5c5da7710
Full Text :
https://doi.org/10.1111/j.1365-2559.2011.04161.x