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Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis: a study of the Osaka Lymphoma Study Group
- Source :
- Histopathology. 60:924-932
- Publication Year :
- 2012
- Publisher :
- Wiley, 2012.
-
Abstract
- Wada N, Zaki M A A, Kohara M, Ogawa H, Sugiyama H, Nomura S, Matsumura I, Hino M, Kanakura Y, Inagaki H, Morii E & Aozasa K (2012) Histopathology 60, 924–932 Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis: a study of the Osaka Lymphoma Study Group Aims: ]Diffuse large B cell lymphoma (DLBCL) occasionally shows an interfollicular pattern of proliferation (DLBCL-IF) preserving lymphoid follicles. In this study, clinicopathological findings in 31 cases of DLBCL-IF were analysed. Methods and results: The study group comprised 20 males and 11 females, with ages ranging from 41 to 87 (median 69) years. The primary site was lymph node in 25 cases, and unknown in six due to advanced stage at diagnosis. Eight cases were clinical Stage I, 10 were Stage II, four Stage III, and nine Stage IV. A polymorphous pattern of proliferation containing large B cells and inflammatory cells was found in about 60% of cases. The overall survival rate of the DLBCL-IF patients was better than that of a DLBCL control group (log-rank test; P
- Subjects :
- Pathology
medicine.medical_specialty
Histology
CD68
General Medicine
Biology
medicine.disease
medicine.disease_cause
Marginal zone
Epstein–Barr virus
Pathology and Forensic Medicine
Lymphoma
medicine.anatomical_structure
immune system diseases
hemic and lymphatic diseases
medicine
Diffuse large B-cell lymphoma
Lymph node
Survival rate
B cell
Subjects
Details
- ISSN :
- 03090167
- Volume :
- 60
- Database :
- OpenAIRE
- Journal :
- Histopathology
- Accession number :
- edsair.doi...........e290d9a61427d38537eb4cc5c5da7710
- Full Text :
- https://doi.org/10.1111/j.1365-2559.2011.04161.x