New Norcucurbitane Triterpenoids from Momordica charantia var. abbreviata

Two new 27-norcucurbitane triterpenoids, 5β,19-epoxy-3β-hydroxy-19( S)-methoxy-27-norcucurbita-6,23( E)-dien-25-one (1) and 3β-hydroxy-25-oxo-27-norcucurbita-6,23( E)-dien-5β,19-olide (2), together with one known cucurbitane triterpene, 5β,19-epoxycucurbita-6,23( E)-diene-3β,25-diol (3), were isolated from the fruits of Momordica charantia var. abbreviata. Their structures were elucidated by spectroscopic methods including EI-MS, 1H, 13C, and 2D NMR data and comparison with the data of known analogues.