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The addition of β-ketoacids to 4-(trifluoromethyl)pyrimidin- 2(1Н)-ones with decarboxylation: an effective method for the synthesis of 4-(2-oxoalkyl)-6-(trifluoromethyl)-3,4-dihydropyrimidin-2-ones
- Source :
- Chemistry of Heterocyclic Compounds. 53:1124-1127
- Publication Year :
- 2017
- Publisher :
- Springer Science and Business Media LLC, 2017.
-
Abstract
- β-Ketoacids reacted with 4-(trifluoromethyl)pyrimidin-2(1Н)-ones according to the mechanism of Michael addition–decarboxylation, forming 4-(2-oxoalkyl)-6-(trifluoromethyl)-3,4-dihydropyrimidin-2-ones.
Details
- ISSN :
- 15738353 and 00093122
- Volume :
- 53
- Database :
- OpenAIRE
- Journal :
- Chemistry of Heterocyclic Compounds
- Accession number :
- edsair.doi...........e33c82757c053ad727c9392802ccaaac