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An autopsy case of aortic dissection due to giant cell arteritis
- Source :
- Pathology International. 71:204-209
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Giant cell arteritis (GCA) is a systemic vasculitis affecting mainly large and medium-sized arteries. GCA sometimes involves the aorta and its major branches and causes aortic dissection as a rare complication. We have experienced an autopsy case of aortic dissection due to GCA. The patient was an 87-year-old Japanese woman with Stanford type A aortic dissection who died 7 days after admission. Two years previously she had been diagnosed as having abdominal aortic aneurysm and undergone endovascular aneurysm repair (EVAR). Although she had no characteristic symptoms of GCA, autopsy revealed marked granulomatous inflammation in the dissected area and coronary arteries. Active arteritis was evident not only in the arteries of the upper extremity but also those in the lower extremity. Granulomatous inflammation was not evident in the aneurysm. The aortic dissection might have been an initial manifestation of GCA. We report the regions of GCA extension and its histology in detail.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
Pathology
medicine.medical_treatment
Autopsy
Endovascular aneurysm repair
Pathology and Forensic Medicine
03 medical and health sciences
0302 clinical medicine
Aneurysm
immune system diseases
medicine.artery
medicine
cardiovascular diseases
Arteritis
skin and connective tissue diseases
Aortic dissection
Aorta
business.industry
General Medicine
medicine.disease
Abdominal aortic aneurysm
Surgery
Giant cell arteritis
030104 developmental biology
030220 oncology & carcinogenesis
cardiovascular system
business
Subjects
Details
- ISSN :
- 14401827 and 13205463
- Volume :
- 71
- Database :
- OpenAIRE
- Journal :
- Pathology International
- Accession number :
- edsair.doi...........e392eb25aea3137d792d7583b3ac5162