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An instructive case of amlodipine‐induced reversible granulomatous CD30 + T‐cell pseudolymphoma

Authors :
Kong Bing Tan
Kah Wai Cheong
Gareth Zigui Lim
Joel Hua-Liang Lim
Source :
Australasian Journal of Dermatology. 61
Publication Year :
2020
Publisher :
Wiley, 2020.

Abstract

We report an unusual case of drug-associated granulomatous CD30+ T-cell pseudolymphoma secondary to amlodipine. A 55-year-old Chinese man presented with a 6-month eruption of disseminated erythematous dermal papulonodules and annular infiltrated plaques over his neck and limbs symmetrically. Histopathology revealed a perivascular and interstitial infiltrate of histiocytes, eosinophils and morphologically normal lymphocytes associated with CD30 expression. The eruption improved rapidly after discontinuation of amlodipine and did not recur.

Details

ISSN :
14400960 and 00048380
Volume :
61
Database :
OpenAIRE
Journal :
Australasian Journal of Dermatology
Accession number :
edsair.doi...........e39c180be8577701a3da7c0902b7fb75
Full Text :
https://doi.org/10.1111/ajd.13240