ChemInform Abstract: REACTION OF ENAMINO KETONE BIDENTATE SYSTEM IN N-SUBSTITUTED 1,2,3,3A,4,5-HEXAHYDRO-6H-INDOL-6-ONES TOWARD SOME NUCLEOPHILIC SPECIES

The reaction of the N-phenylacetyl and N-phenylpropionyl derivatives of 1, 2, 3, 3a, 4, 5-hexahydro-6H-indol-6-one (3 and 10) toward nucleophilic species are described. Several examples demonstrating intermolecular and intramolecular reactions occurring on the two electrophilic sites of the enamino ketone function and potential utility of these reactions on the synthesis of heterocyclic compounds are presented. A possible mechanism to rationalize these products is also presented.