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A multi-component synthesis of N-substituted 2-amino-3-cyano pyrroles via ring-opening of nitroepoxides

Authors :
Jiaan Shao
Liu Xingyu
Zhuang Nie
Wenteng Chen
Yongping Yu
Source :
New Journal of Chemistry. 42:2368-2371
Publication Year :
2018
Publisher :
Royal Society of Chemistry (RSC), 2018.

Abstract

A multi-component synthesis of N-substituted 2-amino-3-cyano pyrroles from nitroepoxides, amines and malononitrile has been demonstrated. The reaction proceeded well for a wide range of nitroepoxides and amines under mild conditions without transition metal catalysis via the formation of three new bonds.

Details

ISSN :
13699261 and 11440546
Volume :
42
Database :
OpenAIRE
Journal :
New Journal of Chemistry
Accession number :
edsair.doi...........e40cf069227759d3b4361a0c90e00bc9
Full Text :
https://doi.org/10.1039/c7nj04584k