Late results of Neo-Adjuvant chemoradiotherapy for primary inoperable non-small cell lung cancer

Locally advanced non-small cell lung cancer keep always a very poor prognosis, because the high risk of metastatic progression despite chemotherapy, and the difficulty to obtain a local control without surgery. Recently, the interaction between 5-FU, Cisplatin and thoracic irradiation led to an increase of clinical response rates. Therefore we conduct a Phase II study of Neo-Adjuvant cyclic concomitant chemoradiotherapy (CCCR) which final results are here reported.