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The Impact of Oxygen on Bacterial Enteric Pathogens
- Publication Year :
- 2016
- Publisher :
- Elsevier, 2016.
-
Abstract
- Bacterial enteric pathogens are responsible for a tremendous amount of foodborne illnesses every year through the consumption of contaminated food products. During their transit from contaminated food sources to the host gastrointestinal tract, these pathogens are exposed and must adapt to fluctuating oxygen levels to successfully colonize the host and cause diseases. However, the majority of enteric infection research has been conducted under aerobic conditions. To raise awareness of the importance in understanding the impact of oxygen, or lack of oxygen, on enteric pathogenesis, we describe in this review the metabolic and physiological responses of nine bacterial enteric pathogens exposed to environments with different oxygen levels. We further discuss the effects of oxygen levels on virulence regulation to establish potential connections between metabolic adaptations and bacterial pathogenesis. While not providing an exhaustive list of all bacterial pathogens, we highlight key differences and similarities among nine facultative anaerobic and microaerobic pathogens in this review to argue for a more in-depth understanding of the diverse impact oxygen levels have on enteric pathogenesis.
- Subjects :
- 0301 basic medicine
Facultative
Anaerobic respiration
biology
030106 microbiology
Bacillus cereus
Virulence
biology.organism_classification
medicine.disease_cause
Campylobacter jejuni
Enterobacteriaceae
Microbiology
03 medical and health sciences
Listeria monocytogenes
Salmonella enterica
Immunology
medicine
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi...........e4c429a3f417f6d9a70b22269850267d