An Enantioselective Synthesis of the Epoxyquinol (+)-Isoepiepoformin

The epoxyquinol natural product (+)-isoepiepoformin (1) has been synthesized for the first time and in an unambiguous fashion by using the scalemic cis-1,2-dihydrocatechol 2 as starting material. The spectroscopic data derived from the synthetic sample of compound 1 match those reported in the literature for the natural product and thereby confirm the structure assigned to the latter.